@article{ACS16807,
author = {Silvia Mariani and Tong Li and Karl Bounader and Dietmar Boethig and Alexandra Schöde and Jasmin S. Hanke and Jana Michaelis and L. Christian Napp and Dominik Berliner and Guenes Dogan and Roberto Lorusso and Axel Haverich and Jan D. Schmitto},
title = {Sex differences in outcomes following less-invasive left ventricular assist device implantation},
journal = {Annals of Cardiothoracic Surgery},
volume = {10},
number = {2},
year = {2021},
keywords = {},
abstract = {Background: Worse outcomes in women compared to men undergoing left ventricular assist device (LVAD) implantation remain an underestimated problem in heart failure (HF) patients. With device miniaturization, less-invasive LVAD implantation techniques have gained relevance, but their impact on outcomes in women is unknown. This study investigates sex-related differences in patients undergoing LVAD implantation through less-invasive procedures.
Methods: This retrospective single-center cohort study included patients who underwent isolated LVAD implantation between 2011 and 2018 through less-invasive techniques. Propensity score matching (PSM) was utilized to balance preoperative heterogeneity. Primary endpoint was two-year survival, and secondary endpoints included long-term survival, surgical outcomes and postoperative adverse events.
Results: Baseline analysis of 191 patients (females 18.3%) showed differences in terms of age [female (median, 52; IQR, 47–61); male (median, 58.5; IQR, 49–66); P=0.005], underlying diagnosis (P},
issn = {2304-1021}, url = {https://www.annalscts.com/article/view/16807}
}