Endovascular therapy in Marfan syndrome: PRO

Marfan syndrome (MFS) is an inherited connective tissue disorder that is associated with arterial fragility and aortic pathologies. The endovascular treatment of patients with MFS is controversial. Published series suggest that while endovascular intervention can be carried out with a low rate of immediate morbidity and mortality, midterm follow up demonstrates sizeable numbers of complications. However, in certain situations—such as rupture, reintervention for patch aneurysms, and elective interventions in which the landing zone is within a previously placed graft—endovascular interventions are appropriate. We present a review of the literature and our institutional perspective on this complex topic.